New research suggests that heavy coffee drinkers have healthier compositions of bacteria in their guts.
New research sheds light on the effect of coffee on the gut microbiota.
More and more research is unpacking the health benefits of drinking coffee. Drinking just one cup may fight off unhealthy fat, ease inflammation associated with obesity, or even protect the brain into old age.
Furthermore, drinking at least three cups of coffee every day may keep arteries healthy and supple by preventing a calcium buildup and staving off the risk of clogging.
Coffee could also help fight off diabetes by improving blood sugar control and can keep the liver healthy and "happy."
But how exactly coffee yields all of these wonderful health benefits has remained somewhat of a mystery.
New research shines some light on the mechanisms behind coffee's effects by looking at the links between coffee and the health of the gut microbiota.
Dr. Li Jiao, from the Baylor College of Medicine in Houston, TX, is the senior and corresponding author of the study.
Dr. Shawn Gurwara, also from Baylor College, who is the first author of the paper, presented the findings at the American College of Gastroenterology (ACG) 2019 Annual Scientific Meeting, which took place in San Antonio, TX.
Looking into the gut microbiota
Dr. Jiao and team set out to examine "the association between caffeine consumption and the composition and structure of the colonic-gut microbiota."
To do so, the scientists asked 34 participants to undergo a screening colonoscopy and endoscopy to confirm the health of their colons.
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The researchers obtained 97 "snap-frozen colonic mucosa biopsies" from various segments of these individuals' colons, extracted microbial DNA, and performed 16s rRNA sequencing analysis.
The participants answered a self-administered food frequency questionnaire to evaluate the daily intake of coffee. The team divided coffee intake into high coffee consumption — that is, at least 82.9 milligrams (mg) per day — and low coffee consumption, that is, less than 82.9 mg daily.